| 2: Laboratory Protocols 2012 - Old J, Harteveld C L, Traeger-Synodinos J, Petrou M, Angastiniotis M, Galanello R• Both types of hemolytic anemia cause the same symptoms | The type of hemoglobin D usually determines the severity of the disease |
|---|---|
| They are intended for healthcare professionals HCPs only | Prevention of Thalassaemias and other Haemoglobin Disorders, Vol 1, 2nd Edition 2013 — Old J, Galanello R, Eleftheriou A, Traeger-Synodinou J, Petrou M, Angastiniotis M• Your doctor may also order this test if you have already been diagnosed with hemolytic anemia |
Alpha-Thalassaemia educational booklet 2007 Eleftheriou A, Angastiniotis M• People inherit Hemoglobin SD disease from their parents.
19| In particular, does your patient take any medications — OTC drugs or Herbals — that might affect the lab results? What are possible complications of hemoglobin E trait? What are the symptoms of hemoglobin E trait? The abnormal hemoglobin is called hemoglobin D | If you inherited the defect from both parents or from 1 parent and a different abnormal hemoglobin from the other parent, it can cause problems, such as:• If both parents have hemoglobin D trait, there is a 25 percent 1 in 4 chance with each pregnancy of having a child with hemoglobin D disease |
|---|---|
| People who have hemoglobin D disease have red blood cells that contain mostly hemoglobin D | Hemoglobin O-Arab is a stable, minimally increased oxygen affinity variant hemoglobin, and O-Arab trait 1 mutated gene is completely silent |
Once the percentage of hemoglobin F is subtracted from the total hemoglobin, the same ratio of hemoglobin O-Arab to hemoglobin A will be observed as in adults.
23