DSM-5 will not include caffeine use disorder, although research shows that as little as two to three cups of coffee can trigger a withdrawal effect marked by tiredness or sleepiness | "Chapter 15: Reinforcement and Addictive Disorders" |
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Long-term caffeine use can lead to mild physical dependence | True compulsive use of caffeine has not been documented |
A withdrawal syndrome characterized by drowsiness, irritability, and headache typically lasts no longer than a day.
There is sufficient evidence to support this as a condition, however it is not yet clear to what extent it is a clinically significant disorder | Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association |
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